The hemodynamics of transcatheter valves are usually excellent, although residual paravalvular aortic regurgitation (usually trivial or mild) is frequent. Stroke, major vascular complications, and conduction disturbances leading to permanent

pacemaker implantation remain among the most-concerning periprocedural complications of TAVI. Nevertheless, promising preliminary data exist for long-term outcomes following TAVI, ‘valve-in-valve’ TAVI for surgical prosthesis dysfunction, and for the treatment of lower-risk patients. Improvements in transcatheter valve technology, optimization of procedural and midterm results, and confirmation of long-term durability of transcatheter valve prostheses will determine the expansion of TAVI towards the treatment of a broader spectrum of patients.”
“Seed dormancy (SD) is an important agronomic trait affecting crop yield and quality. In this study, one rice population of recombinant inbred lines LCL161 (RILs) was used to determine PLX4032 datasheet the genetic characteristics of SD at the early (4 weeks after heading), middle (5 weeks after heading) and late (6 weeks after heading) development stages. The level of SD decreased with the process of seed development, and the SD was significantly affected by the heading date (HD) and temperature at the early and middle development stages. A total of eight additive quantitative trait loci (QTLs) for SD were

identified at three development stages, and more QTLs were expressed at the early and late development stages. Among them, four, one and three additive QTLs were identified at the early, middle and late development stages,

respectively. Epistatic QTLs and QTL-by-development interactions were detected by the joint analysis of multi-development phenotypic values, and one additive and two epistatic QTLs were identified. The phenotypic variation of SD explained by each additive, epistatic QTL and QTL x development interaction ranged from 8.0 to 13.5 %, 0.7 to 3.9 % and 1.3 to 2.8 %, respectively. One major QTL qSD7.1 for SD was tightly linked to the major QTL qHD7.4 for HD, which might be applied to reveal the relationship of SD and HD. By comparing chromosomal positions of RSL3 chemical structure these additive QTLs with those previously identified, five additive QTLs qSD1.1, qSD2.1, qSD2.2, qSD4.1 and qSD4.2 might represent novel genes. The best three cross combinations for the development of RIL populations were predicted to improve SD. The selected RILs and the identified QTLs might be applicable to improve the rice pre-harvest sprouting tolerance by the marker-assisted selection approach.”
“A special procedure of synthesis was developed for amidoaminals of atypical topology through a reduction with i-Bu2AlH of primary products of thermodynamical opening of (3aS,4R,7R,7aS)-3a,4,7,7a-tetrahydro-4,7-epoxy-2-benzofuran-1,3-dione at treating with (-)-alpha-methylbenzylamine.

A diagnosis of primary solitary cutaneous plasmacytoma was made. The lesion was removed surgically, selleck compound and the patient remains in remission up to now. Primary cutaneous plasmacytoma represents only 2%-4% of extramedullary plasmacytomas. The rarity and the nonspecific presentation of cutaneous plasmacytomas does not allow a definite clinical diagnosis. Only histopathology reveals the typical pattern of a dense monomorphic dermal plasmacytic infiltrate, whereas immunohistochemistry shows monoclonality of the neoplastic cells.”
“We studied radiographic features of pulmonary tuberculosis

(PTB) described in the report forms for 907 adolescents from two Brazilian cities. A descriptive analysis showed that the most common radiographic lesions were post-primary tuberculosis (53.3%),

tuberculous expansile pneumonia (27%) and primary complex with adenomegaly (1.8%). Cavitary lesions occurred in 67/243 (27.6%) patients aged 0-15 years and in 116/321 (36.1%) adolescents aged 16-19 years (P = 0.031). Most of the PTB cases had forms similar to those in adults.”
“Obesity is associated with chronic low-grade systemic inflammation. Bariatric surgery has been shown to reduce this inflammation. Here, the effect of a nonsurgical bariatric technique, the duodenal-jejunal bypass liner (DJBL), on systemic inflammation was investigated. Seventeen obese https://www.selleckchem.com/products/elacridar-gf120918.html patients with type 2 diabetes were treated with the DJBL for 6 months. Plasma C-reactive protein (CRP), myeloperoxidase (MPO), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-alpha) were determined prior to and during DJBL treatment. Three months after initiation of DJBL treatment, TNF-alpha levels had increased from 1.8 +/- 0.1 to 2.1 +/- 0.1 pg/mL, whereas IL-6 increased from 2.7 +/- 0.3 to 4.0 +/- 0.5 pg/mL (both p < 0.05). CRP and MPO also increased, though the differences were not significant. After 6 months, the levels of all parameters were similar to baseline levels (CRP, 4.2 +/- 0.6 mg/L; TNF-alpha, 2.0 +/- 0.1 pg/mL; IL-6, 3.5 +/- 0.5 pg/mL; MPO, 53.6 +/- ng/mL;

all p = ns compared to baseline). In the current study, 6 months of endoscopic DJBL treatment did not lead Q-VD-Oph research buy to decreased systemic inflammation.”
“Endometriosis is a disease process characterized by ectopic endometrial tissue. Involvement most commonly occurs in the lower pelvis, outside the uterine cavity, but can occur elsewhere, including the skin. Cutaneous endometriosis is a rare manifestation of this disease, with decidualization occurring in a very small minority of cases, almost always seen in pregnant females. Cutaneous involvement of endometriosis may present a diagnostic problem for the pathologist, particularly in the event of decidualization. Decidualization may mimic a malignancy and as a result may result in unnecessary diagnostic studies for the patient.

The increase in the SFCs in the portal and cardiac samples 30 min after sucrose ingestion was lower in the ELE group than in the control group. The coefficient of correlation between the SFCs in the portal and cardiac samples was 0.825. The peripheral SFC in the control Thiazovivin supplier group progressively increased and was 146 mu mol/L at 60 min. This increase was significantly lower in the ELE group. In contrast, the serum glucose concentrations in the 2 groups were similar. ELE suppressed postprandial hyperfructosemia in the portal, cardiac, and peripheral circulations. ELE may counteract glycation

caused by high blood fructose concentrations induced by the consumption of fructose-containing foods or drinks.”
“Background

Merkel cell carcinoma (MCC) is among the deadliest of cutaneous malignancies. A lack of consensus

evaluation and treatment guidelines has hindered management of this disease. The utility of simultaneous positron emission tomography selleck products and computed tomography (PET/CT) has been demonstrated for a variety of tumors yet remains underinvestigated for MCC.

Objectives

To report the value of fluorodeoxyglucose PET/CT imaging in the initial staging and ongoing management of individuals with MCC and to determine whether any patient or tumor characteristics may predict when PET/CT is more likely to have greater influence on medical decision-making.

Materials and Methods

A single-institution retrospective chart review was conducted of all patients diagnosed with MCC who underwent FDG-PET/CT scanning from 2007 to 2010. The outcome of each of these studies was evaluated as to the influence on patient staging and management. Patient clinical information and information on gross and microscopic tumor characteristics were collected and analyzed.

Results

Twenty patients underwent 39 PET/CT scans.

Results of PET/CT imaging revealed previously unknown information related to MCC in four (20%) patients, leading to changes in management in three of these four cases. Three previously unknown neoplasms were detected.

Conclusion

Fluorodeoxyglucose-positron emission tomography

and computed tomography is a valuable tool for initial staging and to assess response to therapy of patients diagnosed with MCC. https://www.sellecn.cn/products/sch-900776.html Larger prospective studies would be required to establish the optimal timing for this imaging modality.”
“Background: On 1 July 2007 a new transplant law came into force in Switzerland. The principal item of this new law is the change from centre-oriented allocation to patient-oriented national allocation of organs. The aim of the present study is to assess the impact on cold ischaemia time (CIT) and transport requirements.

Methods: From 1 July 2006 to 30 June 2008 168 brain-dead donors were registered by Swisstransplant in Switzerland. Donors have been analysed in a retrospective cohort study design. Donor characteristics, transportation requirements and CIT were assessed from the Necroreport.

Proteoglycans are composites of glycosaminoglycan (GAG) chains attached covalently to specific core proteins. Proteoglycans are expressed ubiquitously on the cell surface, in intracellular compartments, and in the extracellular matrix. GAGs mediate the majority of ligand-binding activities of proteoglycans, and many microbial pathogens elaborate selleck chemical cellsurface and secreted factors that interact with GAGs. Some pathogens also modulate the expression and function of proteoglycans

through known virulence factors. Several GAG-binding pathogens can no longer attach to and invade host cells whose GAG expression has been reduced by mutagenesis or enzymatic treatment. Furthermore, GAG antagonists have been shown to inhibit microbial attachment and host cell entry in vitro and reduce virulence in vivo. Together, these observations underscore the biological significance of proteoglycan-pathogen

interactions in infectious diseases.”
“Transposable elements Temsirolimus cost contribute to the size, structure, variation, and diversity of the genome and have major effects on gene function. Sequencing projects have revealed the diversity of transposable elements in many organisms and have shown that they constitute a high percentage of the genome. PCR-based techniques using degenerate primers designed from conserved enzyme domains of transposable elements can provide quick and extensive surveys, making study of diversity and abundance and their applications possible in species where full genome sequence data are not

yet available. We studied cassava (Manihot esculenta) En/Spm-like transposons (Meens) with regard to genomic distribution, sequence diversity and methylation status. Cassava transposase fragments characteristic of En/Spm-like find more transposons were isolated, cloned and characterized. Sequence analysis showed that cassava En/Spm-like elements are highly conserved, with overall identity in the range of 68-98%. Southern hybridization supports the presence of multiple copies of En/Spm-like transposons integrated in the genome of all cassava cultivars that we tested. Hybridization patterns of HpaII-and MspI-digested cassava genomic DNA revealed highly methylated sequences. There were no clear differences in hybridization pattern between the cultivars. We did not detect RNA transcripts of Meens by Northern procedures. We examined the possibility of recent transposition activities of the cassava En/Spm-like elements.”
“Posterior cranial fossa tumours, not involving the cerebellopontine angle cistern, are a rare cause of trigeminal neuralgia (TN). We describe a patient with a large paramedian tentorial meningioma associated with acquired Chiari malformation who presented with TN. Trigeminal pain resolved after gross total tumour resection and postoperative magnetic resonance images disclosed a minimal residual tumour in the torcular region as well as ascent of cerebellar tonsils.

Results Constant perfusion with carbachol elicited tonic and pulse stimulation with carbachol and oxytocin rhythmic contractions of smooth muscle in the ground reticulum. Under constant perfusion with relaxin the tonic contraction after carbachol was abolished.

CCI-779 molecular weight Conclusions With the novel microperfusion system, isotonic contractions of smooth muscle in the USL can be recorded and quantified in the tissue microenvironment on the microscopic level. The USL smooth muscle is cholinergic, stimulated by oxytocin and modulated by relaxin. Neurourol. Urodynam. 31:12941299, 2012. (C) 2012 Wiley Periodicals, Inc.”
“Purpose of review

To determine the advances made in the genetics of scleroderma in candidate gene association studies.

Recent findings

Over the past 18 months, a number of candidate gene studies using large case-control.. series in scleroderma have been reported. The studies have identified multiple genes involved BAY 73-4506 mouse in immune regulation including BANK1, C8orf13-BLK, IL-23R, IRF5, STAT4, TBX21, and TNFSF4 as susceptibility genes for the development of SSc. Furthermore, gene-gene interaction studies suggest that IRF5, STAT4, and BANK1 as well as TBX21 and STAT4 interact with regard to scleroderma susceptibility. Many of the genetic variants associated with SSc susceptibility are shared among other autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus.

Summary

Candidate

gene association studies have substantially advanced our

understanding of the pathogenesis of SSc and demonstrate that SSc is a polygenic, autoimmune disease.”
“Aims Small molecule library The uterosacral ligament (USL) contains prominent vessels, the function of which is unknown. Here we study the relationship between smooth muscle of the USL and the vascular bundles. Methods Native samples of arteries and vascular bundles were mounted in a perfusion chamber under the stereomicroscope. The effects of noradrenalin, carbachol, oxytocin, and relaxin were monitored by digital time-lapse video and quantified by image processing. Results Arteries were adrenergic and the smooth muscle in the adventitia cholinergic. Relaxin-2 shifted the dose response curve of noradrenalin to the right and widened the arterial lumen within 30?min. Oxytocin induced contraction of the adventitial smooth muscle leading to a slow opening of the artery. In a vascular bundle the differential pattern of both reactivities was demonstrated. Conclusions In the USL the smooth muscle extends into the adventitial layer of blood vessels and forms a functional unit with the vascular plexus, which is regulated by relaxin and oxytocin. Neurourol. Urodynam. 31:13001306, 2012. (C) 2012 Wiley Periodicals, Inc.”
“Purpose of review

Osteoarthritis is the most common form of arthritis in the elderly and is influenced by both genetic and environmental risk factors.

“
“Several lignin-based activated carbon fibers (ACFs) were prepared by initial synthesis of lignin-phenol-formaldehyde (LPF) resins with varied lignin contents, 8-20%, respectively, and then the melt spinning and thermal treatments. Because the guaiacyl groups of lignin reacted with the formaldehyde, the role of lignin played becomes a dominator for controlling the thermal properties of LPF resin and the pore size and related properties of ACFs. GPCR Compound Library high throughput This was proven by the comparison of the scanning electron microscope photographs of all prepared ACFs. FTIR spectra showed that the ACFs were structured

by lignin-contributed carbons. The porosity and adsorption behavior of these ACFs were also studied and compared. Results showed that the ACFs with 14% lignin content have better pore structure and adsorption properties. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 121: 989-994, 2011″
“Cutaneous allodynia is a frequent complaint in migraine patients, possibly induced by central sensitisation of trigeminal nucleus. The objective of this study is to investigate if sleep quality is related to the presence of migraine-associated allodynia. A total of 175 consecutive migraineurs were included, 124 with episodic

and 51 with chronic forms. As control group, 73 subjects free from any kind of headache were included I-BET151 (HC). The presence of allodynia and sleep disturbances was assessed by a set of semi-structured questions. Chi-square test was applied to compare frequencies among groups. Sleep quality was worse among migraineurs with respect to controls for each sleep item analysed. This difference was significant for all items but one (i.e. frequency in drug use to induce sleep). The frequency of sleep disturbances was higher than in controls in both allodynic and non-allodynic migraineurs, although statistical analysis showed that all these differences were still significant in allodynic migraineurs (also in this case for all the sleep items but

one, i.e. frequency in drug use to induce sleep), whilst non-allodynic migraineurs were significantly different from controls only for one item (frequency of initial insomnia). These results suggest that allodynia is strongly related to sleep quality, in a bi-directional Ricolinostat mouse way: sleep disturbances may favour central sensitisation, and, in turn, allodynia may impair sleep.”
“Background: Malaria has been endemic in Linzhi Prefecture in the Tibet Autonomous Region (TAR) over the past 20 years, especially in Motou County with a highest incidence in the country in recent years. Meteorological factors, such as rainfall, temperature and relative humidity in Motou County were unique compared to other areas in Tibet as well as other parts of China, thus the objective of this work was to analyse the temporal correlation between malaria incidence and meteorological factors in Motou County, in order to seek the particular interventions for malaria control.

In the n-type as-grown material, the Z(1/2) (E(C)-0.63 eV) and EH(6/7) (E(C)-1.6 eV) centers are dominant deep levels. At least, seven peaks (IN1, IN3-IN6, IN8, and IN9) have emerged by implantation

and annealing at 1000 degrees C in the DLTS spectra from all n-type samples, irrespective of the implanted species. After high-temperature annealing at 1700 degrees C, however, most DLTS peaks disappeared, and two peaks, IN3 and IN9, which may be assigned to Z(1/2) and EH(6/7), respectively, survive with a high concentration over the implanted atom concentration. In the p-type as-grown material, the D (E(V)+0.40 eV) and HK4 (E(V)+1.4 eV) centers are dominant. Two peaks (IP1 and IP3) have emerged by implantation and annealing at 1000 degrees this website C, and four traps IP2 (E(V)+0.39 eV), IP4 (E(V)+0.72 eV), IP7 (E(V)+1.3 eV), and IP8 (E(V)+1.4 eV) are dominant after annealing at 1700 degrees C in all p-type samples. The IP2 and IP8 may be assigned to the HS1 and HK4 centers, respectively. The depth analyses have revealed that the major deep levels are generated in the much deeper region than the implant profile.”
“We report the case of a patient presenting with incessant monomorphic ventricular tachycardia resistant to antiarrhythmic drugs, and in whom usual percutaneous vascular or pericardial 4EGI-1 molecular weight access

to the left ventricle was hindered by mechanical aortic and mitral prosthetic valves. Because an epicardial location was suspected by electrocardiogram features and because access to the target area through the coronary sinus was not possible, we decided to perform a surgically based radiofrequency (RF) ablation. Catheter mapping of the epicardial

surface through surgical left lateral thoracotomy in the operating room confirmed the epicardial location of the arrhythmogenic substrate and allowed successful RF ablation of the clinically incessant tachycardia. Combined surgical and electrophysiological approach should therefore be performed when RF ablation GDC-0973 chemical structure is needed in case of unadvisable, difficult, or failed nonsurgical percutaneous access. (PACE 2009; 32: 556-560)”
“Background: The analysis of nucleic acids is limited by the availability of archival specimens and the quality and amount of the extracted material. Archived cytogenetic preparations are stored in many laboratories and are a potential source of total genomic DNA for array karyotyping and other applications. Array CGH using DNA from fixed cytogenetic preparations has been described, but it is not known whether it can be used for SNP arrays. Diagnostic bone marrow specimens taken during the assessment of hematological malignancies are also a potential source of DNA, but it is generally assumed that DNA must be extracted, or the specimen frozen, within a day or two of collection, to obtain DNA suitable for further analysis. We have assessed DNA extracted from these materials for both SNP array and array CGH.

Results: Serum levels of KL-6 in NSIP positively correlated with the total HRCT score and overall extent of interstitial disease. Serum levels of SP-D in NSIP showed a positive correlation with the area of ground-glass attenuation without traction bronchiectasis and the inflammatory CT pattern, but the

levels were inversely correlated with the area of ground-glass attenuation with traction bronchiectasis and the fibrotic CT pattern. The follow-up CT and serum marker changes after treatment showed that percent change of disease extent was reflected in both markers, especially KL-6. Further, the decreased fibrotic pattern correlated with both biomarkers. Conclusions: The results indicate that serum levels of KL-6 in NSIP reflect the overall extent of interstitial lesions, which include both inflammatory

and fibrotic lesions, while the levels of SP-D mainly reflect the extent of inflammatory lesions. Copyright Saracatinib (C) 2011 S. Karger AG, Basel”
“Total anomalous pulmonary venous connection with obstruction constitutes a surgical emergency. Medical therapy is palliative GNS-1480 datasheet and unlikely to result in significant or sustained physiologic improvement. Two cases demonstrate the successful use of a novel management scheme in which patients are admitted directly to the operating room for diagnosis confirmation and treatment, obviating the need for time-consuming preoperative assessment in an intensive care unit before surgery.”
“Background: Eosinophilic pleural effusion (EPE) is defined by an eosinophil count of >= 10% in the pleural fluid and often caused by air or blood in the pleural space. The diagnostic significance of EPEs is still a matter of debate. Objective: The objective of this study was to systematically review the medical literature to evaluate the diagnostic significance of EPEs. Methods: Electronic databases were searched from 1950 to April 2010 to perform a meta-analysis. Data were extracted using standardized forms, and pooled odds ratios

with 95% confidence intervals were calculated. A logistic regression analysis was also performed to evaluate the association between the pleural eosinophil counts and the likelihood AZD4547 datasheet of underlying causes of EPEs. Results: We identified a total of 687 cases of EPE. The most common cause of EPEs was malignancy (26%) followed by idiopathic (25%) and parapneumonic (13%) effusions. The likelihood of malignancy or tuberculosis was somehow lower in EPEs than in non-EPEs, but the differences were not statistically significant. The prevalence of malignancy was significantly lower in the group of patients that required a pathologic confirmation (21 vs. 30%; p = 0.01). The likelihood of malignancy was inversely correlated with the pleural fluid eosinophil counts. The likelihood of idiopathic effusion was significantly higher in EPEs than in non-EPEs. Conclusions: Malignancy was the most common cause of EPEs.

“
“A self-powered, hybrid sensor integrating a resonant microfabricated antenna with a spin valve sensor was fabricated. The device was activated by a radio frequency (RF) external electromagnetic source. This hybrid device was designed to behave as a series resonant circuit at 130 MHz. The self-powered sensor (powered by the RF field through the antenna) was capable of measuring the amplitude of the perpendicular RF excitation field crossing the antenna, down to 2.5 mu T when excited with a RF field of

130 MHz. (C) 2011 American Institute of Physics. [doi:10.1063/1.3537816]“
“A simplified model Panobinostat ic50 is developed to calculate the modulus of carbon black filled rubber compounds by using standard characterization data selleck chemicals llc of the filler, its volume fraction and only one fitting parameter: the number of junctions between

neighboring carbon black aggregates. The model is based on three hypotheses with respect to (1) the optimal dispersion of aggregate, (2) the pure physical nature of rubber-carbon black interactions, and (3) the possibility to describe aggregates essentially in terms of specific surface area and structure, both accessible through standard characterization methods. Average rubber-filler interactions are introduced through microme-chanical considerations. The model is probed by using dynamic strain sweep test results on two series of carbon filled compounds, one on the basis of SBR1500 Emulsion Styrene-Butadiene Rubber, the other on RSS3 Natural Rubber. It is found that the number of junctions is decreasing with increasing strain amplitude, thus, offering a clear explanation for the well known dynamic strain softening effect. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 122: 599-607, 2011″
“Leflunomide is effective and well tolerated in the treatment of rheumatoid arthritis (RA), however, data on its use in early RA are scarce. This study seeks to evaluate effectiveness and safety of leflunomide in the treatment of early RA in daily practice. This

prospective, open-label, non-interventional, multi-center study was carried out over 24 weeks including adults with early RA (a parts per thousand currency sign1 year since diagnosis). Leflunomide treatment was according to label instructions. Three hundred thirty-four patients were included. Disease activity score in 28 joints (DAS28) response (reduction in DAS28 of > 1.2 selleck chemical or reduction of > 0.6 and a DAS28 of a parts per thousand currency sign5.1) was 71.9% at week 12 and 84.6% at week 24. 25.0% of patients achieved clinical remission (DAS28 a parts per thousand currency signaEuro parts per thousand 2.6). Most frequently reported adverse drug reactions (ADR) were diarrhea (3.0%), nausea (2.4%), hypertension (1.8%), and headache (1.5%). Serious ADR were reported in four patients (1.2%). Leflunomide showed the effectiveness which was to be expected from controlled studies without revealing any new or hitherto unknown side effects.

05). No significant differences were observed in the contents of total saturated fatty acids and monounsaturated fatty acids, or the ratio of n-3/n-6 fatty acids among the large yellow croakers of the two age groups. We conclude that large yellow croakers are good food sources of EPA and DHA.”
“This article presents a simple deroofing technique to retrieve a broken

endodontic file lodged in the JNJ-64619178 solubility dmso mandibular canal and causing dysesthesia with pain. Many unsuccessful attempts were made to retrieve the broken instrument. The deroofing technique described is simple, requiring local anesthesia and done on an outpatient basis with minimum morbidity. A brief review of the literature on dysesthesia of the inferior alveolar nerve caused by endodontic materials is also presented. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;111:e48-e51)”
“A 13-year-old boy presented with the overall phenotypic and genotypic characterisation of Schwarz-Jampel syndrome (SJS). Windswept deformity was a major orthopaedic abnormality. Prompt diagnostic measures

were applied to this patient associated with several orthopaedic procedures to move closer to acceptable appearance and function.”
“The magnetocaloric effect of La0.45Sr0.55MnO3 nanoparticles was studied by dc magnetization measurements. A sample with mean particle size of about 140 nm exhibits both a conventional magnetocaloric effect around the Curie temperature (approximate to 295 K) and a large inverse magnetocaloric effect around the antiferromagnetic-ferromagnetic transition temperature (approximate to AZD1480 mw 200

K). The change of magnetic entropy increases monotonically with applied magnetic field and reaches the values of 5.51 J/kg K and – 2.35 J/kg K at 200 K and 295 K, respectively, in an applied field of 5 T. The antiferromagnetic-ferromagnetic transition is absent in a 36 nm size sample, which shows only a broad ferromagnetic GSI-IX concentration transition around 340 K and a small change in magnetic entropy near room temperature. The results are discussed in terms of the entropy difference between the A-type antiferromagnetic ground state of La0.45Sr0.55MnO3 and the low moment ferromagnetic state. By comparing the results obtained on nanoparticles and bulk La0.45Sr0.55MnO3, one can conclude that the inverse magnetocaloric effect in a material showing the antiferromagnetic-ferromagnetic transition could be improved over a wide range of temperature by tuning the spin disorder in the antiferromagnetic state. (C) 2011 American Institute of Physics. [doi:10.1063/1.3614586]“
“Making sense of rapidly evolving evidence on genetic associations is crucial to making genuine advances in human genomics and the eventual integration of this information in the practice of medicine and public health. Assessment of the strengths and weaknesses of this evidence, and hence the ability to synthesize it, has been limited by inadequate reporting of results.