The median number of magnification images was 11 in each method. The average observation http://www.selleckchem.com/products/Adrucil(Fluorouracil).html time (±SD) for magnification was 99.9 ± 64.1 s in NFM and 91.5 ± 64.6 s in CMM (p = 0.54), respectively. Judgments
of image quality in mucosal microsurface structure were 4.09 ± 0.39 in NFM and 3.73 ± 0.40 in CMM (p = 0.015). Those in subepithelial microvascular architecture were 3.53 ± 0.45 in NFM and 4.29 ± 0.45 in CMM (p = 0.001). Judgement of clear demarcation line were 3.91 ± 0.41 in NFM and 3.61 ± 0.54 in CMM (p = 0.089). Conclusion: The near focus method seems to be a useful method for magnification in the early stage of gastric epithelial tumors. Further evaluation of this novel technology is necessary. Key Word(s): 1. Magnification; 2. gastric epithelial tumor; 3. method Presenting Author: BING HU Additional Authors: WEI LIU Corresponding Author: HUI LIU Affiliations: West China Hospital, Sichuan University Objective: To evaluate the natural course of asymptomatic EUS-suspected
gastric gastrointestinal stromal tumors (GISTs) of ≤30 mm in size, selleck chemical and to assess a basis of the optimal management of incidentally detected, asymptomatic small EUS-suspected GISTs. Methods: The data of patients diagnosed as asymptomatic small gastric GISTs by endoscopic ultrasound (EUS) at West China Hospital, Sichuan University, between January 2004 and December 2013 were included in this study. A small EUS-suspected gastric GISTs was defined as a hypoechoic
lesion arising from the muscularis propria (fourth layer) or submucosa medchemexpress (third layer) of gastric wall on endoscopic ultrasound. The natural course of gastric GISTs was evaluated by EUS. A >25% increase in the maximal diameter, and/or echo patterns change, and/or ulceration of the tumors were defined as a significant change. Univariate analysis and multivariate analysis using Cox proportional hazard model were carried out to evaluate the changes in GISTs (changes in tumor size, echo pattern, ulceration) with initial related factors of the lesions. Optimal management of asymptomatic small GISTs were reviewed for subsequent analysis. Results: Two hundred and ten patients were included in this study. There were 88 men (41.9%), and the mean age was 55.19 ± 11.29 years old (range, 20–84 years). The median follow-up for the 210 cases was 37 months (range, 6–89 months), and changes in size, and/or echo patterns change, and/or ulceration were found in 9 cases (4.28%) at a median follow-up of 32.5 months. Forty two patients underwent surgical/endoscopic resection; of these, 40 cases (95.2%) were diagnosed as gastric GISTs, of which 3 patients were considered at intermediate risk, 28 at low risk, and 9 at very low risk. In a univariate analysis using log-rank test, a change in tumor did not show a statistical significance by initial size (≤10 mm, 4.