This paper presents the translation, adaptation and validation of the GTS-QOL for young Italian patients with GTS.\n\nMETHODS: A three-stage process involving 75 patients with GTS recruited through three Departments p53 inhibitor of Child and Adolescent Neuropsychiatry in Italy led to the development of a 27-item instrument (Gilles de la Tourette Syndrome-Quality of Life Scale in children and adolescents, C&A-GTS-QOL) for the assessment of HR-QOL through a clinician-rated interview for 6-12 year-olds and a self-report questionnaire for 13-18 year-olds.\n\nRESULTS: The C&A-GTS-QOL demonstrated satisfactory scaling assumptions and acceptability.

Internal consistency reliability was high (Cronbach’s alpha > 0.7) and validity was supported by interscale correlations (range 0.4-0.7), principal-component factor analysis and correlations with other rating scales and clinical variables.\n\nCONCLUSIONS: The present version of the C&A-GTS-QOL is the first disease-specific HR-QOL tool for Italian young patients with GTS, satisfying criteria for acceptability, reliability and AZD8186 manufacturer validity.”
“This study dealt with the anxiety reactions in women who elected to have an abortion as compared with women who chose to carry to term. The sample comprised 140 women, 70 of whom chose to abort and 70 women who carried to term serving as a control group. The results

of this study indicated higher rates of anxiety in women who chose to terminate their pregnancies. We also examined some demographic predictive factors that might have had an influence on anxiety levels. The only factor that reached statistical significance was the socioeconomic status of the women. The impact of other factors

(age, marital status and educational level) was negligible. The authors propose a wider use of counseling psychological services in the obstetrics and gynecology clinics.”
“Objective: The complex chronic patient program (CCP) of the Alt Penedes aims to improve the coordination of care. The objective was to evaluate the relationship between the costs associated with the C188-9 purchase program, and its results in the form of avoided admissions. Design: Dost-effectiveness analysis from the perspective of the health System based on a before-after study. Location: Alt Penedes. Main measurements: Health services utilisation (hospital [admissions, emergency visits, day-care hospital] and primary care visits). CCP Program results were compared with those prior to its implementation. The cost assigned to each resource corresponded to the hospital CatSalut’s concert and ICS fees for primary care. A sensitivity analysis using boot strapping was performed. The intervention was considered cost-effective if the incremental cost-effectiveness ratio (ICER) did not exceed the cost of admission ((sic)1,742.01). Results: 149 patients were included. Admissions dropped from 212 to 145.