The vascular network was thickening, extending, tortuous and twisted. Gastric varices were thickening and twisted in neoplasia. Superior mesenteric veins and spleen kidney appeared to be normal. The splenic GW-572016 supplier artery in arterial phase could be seen to be thickening and twisted. CT diagnosis: The nature of pancreasthe tail area to be determined.

And the causes were unknown of portal hypertension secondary to splenic vein, left gastric vein, varices, splenomegaly, and the twisted splenic artery. Results: On August 24, the patient vomited again about 600 ml of bright-red blood and solutioned about 400 ml of bright -red bloody stools. Emergency operation: in the operation there were no obvious gastroesophageal varices, measuring about 28 cm water column of portal vein pressure. There was no liver nodular cirrhosis but apparent spleen surface inflammation, covered with yellow pus and wrapped partially with omental tissue hyperemia. There were apparent congestion and edema in pancreatic tail, with the hard mass of the size of 2 cm × 2.5 cm × 1.5 cm. After removing the mass and separating perisplenic adhesion,

and then through splenectomy and gastric body longitudinal incision, gastric mucosal erosion could be seen without active bleeding; and about 200 ml of old blood clot was seen instead of ulcer or tumor. Post-operative diagnosis: Venetoclax research buy regional portal hypertension, splenomegaly, spleen periodontitis, pancreatic tail inflammation. Postoperative pathology: pancreatic

inflammation. Conclusion: Pancreatic portal hypertension is a rare disease, belonging to regional portal hypertension, caused by spleen venous obstruction. Splenic vein is parallel with the pancreas. Pancreatic diseases include chronic pancreatitis, pancreatic pseudocyst, and pancreatic tail tumor, which will compress and distort the splenic vein, cause the thickening of the vessel wall or intraluminal obstruction, and effect the splenic vein reflux, finally leading to increased venous pressure in the stomach area. Since the portal and mesenteric venous pressures are normal, resulting in the splenomegaly and collateral PD-1 inhibitor circulation in the stomach area, the latter of which is characterized by such clinical manifestations as the short gastric vein, left gastroepiploic vein, and gastric varices of esophageal varices. Gastric varices manifest themselves much more often than esophageal varices do. The disease in clinical practice has four characteristics: (1) a medical history of pancreas; (2) gastric or (and) lower esophageal varices; (3) splenomegaly; (4) normal liver function. The key to the diagnosis of pancreatic portal hypertension is to find out gastroesophageal varices without symptoms of liver disease. Pancreatic portal hypertension should be taken into more consideration especially for sole gastric varices. This patient in the treatment process had repeatedly undergone endoscopy examinations without being detected the gastric fundus hemorrhage.