Recurrence of NHL at sites of macroscopic disease remains common despite HDC. IF-RT achieves excellent local regional control and consolidative IF-RT after ASCT seems indicated, particularly in patients with bulky disease. In the absence of a prospective randomized trial and proven impact on survival rates, IF-RT can be recommended as an option post-ASCT to enhance Mocetinostat in vivo local disease control. Copyright (C) 2007
John Wiley & Sons, Ltd.”
“Background: Rhythm disturbances are a frequent clinical manifestation of depression. In recent years a possible relationship between depression and chronotypes has emerged. Specifically eveningness has been proposed as vulnerability factor. The aim of this study was to describe sleep features of depressed patients according to chronotypes and to explore possible associations with the clinical features of depressive episodes.\n\nMethods: 100 patients diagnosed with Major Depressive Disorder according to the Mini International Neuropsychiatric Interview (MINI) were included (age: 34 +/- 11.74, range: 18-60 years; female/male:79/21). At admission the Hamilton Rating Scale for Depression (HRSD) was administered. Patients were also administered the Morningness-Eveningness Questionnaire (MEQ), the Epworth Sleepiness Scale, the Athens Insomnia Scale and the Pittsburgh
Sleep Quality Index.\n\nResults: According to MEQ scores patients were classified in three groups: a) eveningness (n = 18), b) neither (n = 61) and c) morningness type (n = 21). ACY-738 in vivo The age was different among chronotypes, being morningness-type patients older. The eveningness-type
group showed higher scores in suicidal thoughts, more impaired work and activities, higher paranoid symptoms, higher scores on the anxiety cluster (HRSD), while the morningness-type group showed lower proportion of melancholic symptoms (MINI). We did not find association between sleep parameters and specific chronotypes.\n\nLimitations: The relatively small sample size and the concurrent assessment of chronotypes and depression may have biased our findings.\n\nConclusions: Our data suggest the idea that chronotypes have an impact on depressive episodes features, with higher severity for the eveningness-type. (C) Selleck Autophagy inhibitor 2009 Elsevier B.V. All rights reserved.”
“Aims:\n\nTo explore the effect of Lactobacillus on redox state of colon chyme.\n\nMethods and Results:\n\nNine Lactobacillus strains were studied for the inhibition of lipid peroxide formation in Fe2+/ascorbate system and for their ability to chelate ‘free’ ferrous ion. The result shows both properties were strain specific and no relationship between them was found. Both properties of Lactobacillus paracasei Fn032, Lactobacillus rhamnosus GG (LGG) and Lactobacillus sp. Fn001 were successively decreasing.