Advanced maternal age and newborn weight were directly related, whereas time of labor, Bishop score and parity were inversely related to a higher cesarean rate.

Conclusions: When single indication of induction of labor with prostaglandins is considered, advanced maternal age represents a significant independent risk factor for cesarean delivery.”
“Purpose of review

Recent studies suggest

that extracranial involvement of giant Dorsomorphin in vitro cell arteritis (GCA) may be more extensive than previously appreciated and clinicians should be aware of this complication.

Recent findings

Imaging studies in GCA and polymyalgia rheumatica (PMR) suggest that vasculitis can affect multiple vascular territories including the lower extremities. The findings of imaging studies, clinical features and outcomes of patients with lower extremity vasculitis are explored in this review. Possible mechanisms for the observed

distribution of vessel involvement are discussed.

Summary

Lower extremity involvement in GCA and PMR may be associated with significant morbidity and is likely underrecognized clinically. Imaging studies can be useful in identifying this uncommon phosphatase inhibitor library complication.”
“Objective: To investigate prematurity rate in women aged >= 45 carrying a twin pregnancy. Other maternal and neonatal outcomes are also described.

Design: Retrospective cohort study.

Setting: Women delivering a twin pregnancy at a single tertiary medical center.

Population: The study included all women aged 45 years and over carrying a twin pregnancy who delivered at 20 weeks gestation or beyond over a 9-year period from May 2000 to May 2009.

Methods: Women aged 45 years and over

were identified, AG-881 cost all conceived by in vitro fertilization with ovum donation. The study group was compared to a control group of women <40 years with twin pregnancies conceived by IVF who delivered during the same time period.

Main outcome measure(s): Maternal complications during pregnancy and neonatal outcome.

Results: During the study period 32 women >= 45 years delivered twins. The control group included 109 women. The rate of delivery before 37 weeks as well as before 32 weeks were very high in our study group (65% versus 40%, p = 0.01 and 15% versus 5.0%, p = 0.05, respectively). The rate of maternal life-threatening complications including blood product transfusion and maternal admission to the intensive care unit were also significantly higher in our study group compared to the control group (18% versus 2%, p = 0.018 and 6.3% versus none, p = 0.05).

Conclusions: Women >= 45 years old with twin pregnancy carry a higher risk of maternal and perinatal complications.”
“Purpose of review

Granuloma formation in giant cell arteritis (GCA) emphasizes the role of adaptive immunity and highlights the role of antigen-specific T cells.