The current study was conducted on a group of peritoneal dialysis patients to learn how the response

to hepatitis B virus vaccination varies according to the patient’s clearance of urea normalized to total body water (Kt/V).\n\nMETHODS: A convenience sample of 33 peritoneal dialysis patients (13 women and 20 men, with a mean age of 49 +/- 12 years) was administered double doses (20 mu g IM in each deltoid muscle) of recombinant hepatitis B vaccine at 0, 1, 2, and 6 months. Response to immunization was measured at one to three months after the final dose of vaccine. The subjects were divided into groups according to the level of antibodies to hepatitis B surface www.selleckchem.com/products/lonafarnib-sch66336.html antigen (anti-HBs), including non-responders (<10 IU/L), weak responders (10-100 IU/L), and good learn more responders (>100 IU/L).\n\nRESULTS: Among non-responders, weak responders, and good responders, significant differences were found in age (54 +/- 12 vs. 56 +/- 9 vs. 45 +/- 12 years, respectively; p = 0.049)

and recombinant human erythropoietin use (20 vs. 29 vs. 76%, respectively; p = 0.016). No significant differences in weekly total Kt/V (p = 0.704), weekly peritoneal Kt/V (p = 0.064) and residual glomerular filtration rate (p = 0.355) were found across the three groups.\n\nCONCLUSIONS: Delivered clearance measured by weekly peritoneal Kt/V and total clearance measured by weekly total Kt/V did not predict the response to hepatitis

B virus vaccination in patients on peritoneal dialysis.”
“Takayasus arteritis is a chronic, idiopathic, medium and large vessel vasculitis involving aorta and its main branches. Frequent neurological manifestations include postural syncope, seizures, and blindness. Stroke, as presenting feature of Takayasus arteritis, is unusual. CT angiography reveals characteristic involvement of aortic arch and its branches. Involvement GSK1838705A of intracranial vasculature is rather unusual. We are describing an unusual patient of Takayasus arteritis who presented with recurrent disabling syncopal attacks and had extensive involvement of intracranial vasculature. CT angiography revealed severe involvement of aortic arch. There was near complete occlusion at origins of both subclavian arteries, distal flow was maintained by collateral vessels along the chest wall. There was near total occlusion (at origin) of right common carotid with normal flow in distal part. The left common carotid was more severely involved showing greater than 80 narrowing in proximal half of the vessel. CT angiography also revealed involvement of left internal carotid artery, narrowing of left middle cerebral artery and involvement of cortical vessels. Patient was treated with oral corticosteroids. She improved remarkably after two and half months of follow up.