Overall, severe

Overall, severe trauma affected adults: 4206 cases in age 0–45, 7495 cases after 45 years. Mortality increased with age, reaching nearly 50% in trauma victims older than 75 years. Similarly, hospital and ICU-LOS, rate of admission to ICU and reimbursed DRG, all increased with age, with the higher levels in ages between 13 and 74 years. On the contrary,

pediatric cases (age group 0–12) were Selleck Ro 61-8048 only 482 in three years, with shorter ICU LOS, decreased mortality and lower levels of reimbursement. All of these differences were statistically significant (p < .0001, ANOVA). Table 2 Severe trauma hospitalized in Lombardia according age groups

  Modality of trauma: absolute values Age groups Number Deceased %_ deceased LOS (±SD) % ICU adm ICU LOS (±SD) Avg remb (€) (±SD) 00-06 322 15 4.65 10.65 (15.22) 79.165 3.36 (7.49) 6˙588.98 (11828.14) 07-12 160 4 2.50 12.50 (12.74) 88.75 3.88 (7.81) 7˙492.89 (10229.22) 13-17 411 19 4.62 17.20 (15.94) 95.38 6.39 (9.20) 12˙908.43 (16509.47) 18-45 3313 334 10.08 20.88 (21.35) PSI-7977 clinical trial 93.96 7.66 (11.25) 16˙144.73 (19550.47) 46-64 2148 356 16.57 21.01 (22.31) 85.52 7.57 (12.74) 16˙207.54 (21784.13) 65-74 1657 407 24.56 20.39 (21.06) 74.83 7.13 (11.93) 16˙224.24 (21679.17) >74 3690 1693 45.88 15.21 (16.34) 45.85 3.74 (9.20) 10˙067.29 (16701.65) All differences significant (p < .0001) at Rolziracetam ANOVA. In

three cases age informations have been missed. The cause of accident has been indicated in 72.98% of cases (Tables 3 and 4) and “other mechanism”, road-related trauma, injured in domestic pertinences and at workplace were the principal conditions. As expected, accidents on the road and at the workplace were the principal causes of trauma for males aging from 18 to 64 years. On the contrary, accidents in domestic pertinences increased with age, being the principal cause of trauma after 64 years, and old women were affected the most. Ipatasertib supplier violence inflicted by others (assault) or self-inflicted violence was rare in Lombardia and affected people 18 to 64 years old. In pediatric age most of cases were domestic or road-related. Statistic analysis demonstrated a significant association at chi-square test between gender and modality of trauma: males had more occupational injuries, trauma on the road and injuries caused by violence by others, while females were more subjected to domestic injuries and self inflicted violence.

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