Lancet. 2007;369:381–8.PubMedCrossRef
13. Fishbane S, Besarab A. Mechanism of increased mortality risk with erythropoietin treatment to higher hemoglobin targets. Clin J Am Soc Nephrol. 2007;2:1274–82.PubMedCrossRef 14. Fukuma S, Yamaguchi T, Hashimoto S, Nakai S, Iseki K, Tsubakihara Y, Fukuhara S.: Erythropoiesis-stimulating agent responsiveness and mortality in hemodialysis patients: results from a cohort study from the Dialysis Registry in Japan. Am J Kidney Dis. 2012 59(1) 108−16. 15. Kilpatrick RD, Critchlow CW, Fishbane S, Besarab A, Stehman-Breen C, Krishnan M, Bradbury BD. Greater epoetin alfa responsiveness is associated with improved survival in hemodialysis patients. Clin J Am Soc Nephrol. 2008;3:1077–83.PubMedCrossRef 16. Crenigacestat chemical structure Locatelli F, Aljama P, Canaud B, Covic A, De Francisco Bucladesine cell line A, Macdougall IC, Wiecek A. On behalf of the Anaemia Working Group of European Renal Best Practice (ERBP).: target haemoglobin to aim for with erythropoiesis-stimulating agents: a position statement by ERBP following publication of the Trial to Reduce Cardiovascular Events with Aranesp(R) Therapy (TREAT) Study. Nephrol Dial Transplant. 2010;25:2846–50.PubMedCrossRef 17. Besarab A, Coyne DW. Iron supplementation to treat anemia in patients with chronic kidney disease. Nat Rev Nephrol. 2010;6:699–710.PubMedCrossRef 18. Drüeke T. Hyporesponsiveness to recombinant
human erythropoietin. Nephrol Dial Transplant. 2001;16:25–8.PubMedCrossRef 19. Macdougall IC, Chandler G, Elston O, Harchowal J. Beneficial effects of adopting an aggressive intravenous iron policy in a hemodialysis unit. Am J Kidney Dis. 1999;34:S40–6.PubMedCrossRef 20. Macdougall IC. Monitoring of iron status and iron supplementation in patients treated with erythropoietin. Curr Opin Nephrol Hypertens. 1994;3:620–5.PubMedCrossRef 21. Hörl WH, Cavill I, MacDougall IC, Schaefer RM, Sunder-Plassmann G. How to diagnose and correct Acetophenone iron deficiency
during r-huEPO therapy–a consensus report. Nephrol Dial Transplant. 1996;11:246–50.PubMedCrossRef 22. Horl WH. Clinical aspects of iron use in the anemia of kidney disease. J Am Soc Nephrol. 2007;18:382–93.PubMedCrossRef 23. Cavill I. Intravenous iron as adjuvant therapy: a two-edged sword? Nephrol Dial Transplant. 2003;18:24–8.CrossRef 24. Eschbach JW, Egrie JC, Downing MR, Browne JK, Adamson JW. Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial. N Engl J Med. 1987;316:73–8.PubMedCrossRef 25. Macdougall IC, Hutton RD, Cavill I, Coles GA, Williams JD. Poor response to treatment of renal anaemia with erythropoietin corrected by iron given intravenously. BMJ. 1989;299:157–8.PubMedCrossRef 26. Aronoff GR. Safety of intravenous iron in clinical practice: implications for anemia management protocols. J Am Soc Nephrol. 2004;2:99–106. 27.