Individuals with the

condition first experience severe pain across the shoulder and upper arm. Within a few hours or days, weakness, wasting (atrophy), and paralysis may affect the muscles of the shoulder. Although individuals with the condition may experience paralysis of the affected areas for months or, in some cases, years, recovery is usually eventually complete.”
“OBJECTIVE: Nerves of the pelvic plexus and lower abdominal wall can lead to chronic neuralgias owing to a variety of causes, including iatrogenic injury, trauma, tumors, and primary nerve entrapment. Differentiating among the various neural etiologies can be a challenging task. Here, we present a large series of patients who underwent surgical GSK621 treatment of these nerves, with an emphasis on diagnostic and therapeutic considerations.

METHODS: Between 1970 and 2006, the senior authors (DGK and DHK)

surgically treated 264 cases of neuralgia of the pelvic plexus and nerves. A retrospective analysis of the patients’ history, physical, diagnostic examinations, and follow-up was performed.

RESULTS: Twenty-five cases of solely ilioinguinal neuralgia and 24 cases of combined ilioinguinal Blasticidin S purchase neuralgias were treated. Of these, iatrogenic injury was the most common etiology. One hundred forty-five patients underwent surgical exploration for either femoral nerve injury (119 EPZ015666 manufacturer patients) or lateral femoral cutaneous compression (26 patients). Seventy-five percent of patients had femoral nerve injuries attributable to trauma (iatrogenic versus penetrating injuries), and the remaining 25% of patients had cystic masses or tumors. Fifty-two masses of the pelvic plexus were

treated, including neurofibromas (68%), schwannomas (18%), malignant nerve sheath tumors (5%), and non-neural sheath tumors (9%).

CONCLUSION: Effective surgical management of these complex neuralgias depends on a solid understanding of the surgical anatomy and proper diagnosis. Electromyography and local anesthetic blocks not only can provide insight into the diagnosis but also have predictive value in assessing which patients may benefit from neurectomy or neurolysis.”
“OBJECTIVE: The purpose of this review is to summarize the basic science literature related to chronic nerve injuries, and to then use this as the background to provide emerging insights into the promising role of cellular therapy for nerve injury repair.

METHODS: The literature pertinent to the experimental and clinical aspects of chronic nerve injury was reviewed, as was emerging literature and our own recent experience in using cellular therapy to repair injured nerves.

RESULTS: Peripheral nerves have the potential to regenerate axons and reinnervate end organs. Yet, outcome after peripheral nerve injury, even after nerve repair, remains relatively poor.