In Fire blight: the disease and its causative agent, Erwinia amylovora. Oxon, UK: CABI Publishing; 2000.CrossRef 4. Bonn WG, Van der Zwet T: Distribution and economic importance of fire blight. In Fire blight: the disease and its causative agent,

Erwinia amylovora. Oxon, UK: CABI Publishing; 2000:37–53.CrossRef 5. McManus PS, Stockwell VO, Sundin GW, Jones AL: Antibiotic use in plant agriculture. Annu Rev Phytopathol 2002, 40:443–465.PubMedCrossRef 6. Nikaido H: Multidrug efflux pumps of gram-negative bacteria. J Bacteriol 1996, 178:5853–5859.PubMedCentralPubMed 7. Walsh C: Molecular mechanisms that confer antibacterial drug resistance. Nature 2000, 406:775–781.PubMedCrossRef 8. Piddock LJ: Multidrug-resistance efflux pumps – not just for resistance. Nat Rev Microbiol 2006, 4:629–636.PubMedCrossRef 9. Pos K: Trinity BAY 11-7082 selleckchem revealed: Stoichiometric complex assembly of a bacterial multidrug efflux pump. Proc Natl Acad Sci U S A 2009, 106:6893–6894.PubMedCentralPubMedCrossRef 10. Nakamura H: Gene-controlled resistance to acriflavine and other basic dyes in Escherichia coli . J Bacteriol 1965, 90:8–14.PubMedCentralPubMed

11. Nikaido H: Antibiotic resistance caused by gram-negative multidrug efflux pumps. Clin Infect Dis 1998,27(Suppl 1):S32-S41.PubMedCrossRef 12. Ma D, Cook DN, Alberti M, Pon NG, Nikaido H, Hearst JE: Molecular cloning and characterization of acrA and acrE genes of Escherichia coli . J Bacteriol 1993, 175:6299–6313.PubMedCentralPubMed 13. Rosenberg EY, Ma D, Nikaido H: AcrD of Escherichia coli is an aminoglycoside efflux pump. J Bacteriol 2000, 182:1754–1756.PubMedCentralPubMedCrossRef 14. Elkins CA, Nikaido H: Substrate specificity of the RND-type multidrug efflux pumps AcrB and AcrD of Escherichia coli is determined predominantly by two large periplasmic loops. J

Bacteriol 2002, 184:6490–6498.PubMedCentralPubMedCrossRef 15. Poole K, Krebes K, McNally C, Neshat S: Multiple antibiotic resistance in Pseudomonas aeruginosa : evidence for involvement of an efflux operon. J Bacteriol 1993, 175:7363–7372.PubMedCentralPubMed 16. Burse A, Weingart H, Ullrich MS: The phytoalexin-inducible multidrug efflux pump AcrAB contributes to click here virulence in the fire blight pathogen, Erwinia amylovora . Mol Plant-Microbe Interact 2004, 17:43–54.PubMedCrossRef 17. 2-hydroxyphytanoyl-CoA lyase Al-Karablieh N, Weingart H, Ullrich MS: Genetic exchange of multidrug efflux pumps among two enterobacterial species with distinctive ecological niches. Int J Mol Sci 2009, 10:629–645.PubMedCentralPubMedCrossRef 18. Grkovic S, Brown MH, Skurray RA: Regulation of bacterial drug export systems. Microbiol Mol Biol Rev 2002, 66:671–701.PubMedCentralPubMedCrossRef 19. Nishino K, Honda T, Yamaguchi A: Genome-wide analyses of Escherichia coli gene expression responsive to the BaeSR two-component regulatory system. J Bacteriol 2005, 187:1763–1772.PubMedCentralPubMedCrossRef 20.